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http://purl.uniprot.org/citations/16112859http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16112859http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16112859http://www.w3.org/2000/01/rdf-schema#comment"The 17-membered phenylalanine-based macrocycle 6 was prepared starting from 3-iodo-phenylalanine. Macrocyclization of alkene phenyl iodide 5 was effected through a palladium-catalyzed Heck reaction. The macrocyclic alpha-ketoamides were active inhibitors of the HCV NS3 protease, with the C-terminal acids and amides being more potent than tert-butyl esters."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2005.07.033"xsd:string
http://purl.uniprot.org/citations/16112859http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2005.07.033"xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Madison V."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Madison V."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Chen K.X."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Chen K.X."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Girijavallabhan V."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Girijavallabhan V."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Prongay A."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Prongay A."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Njoroge F.G."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Njoroge F.G."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Pichardo J."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/author"Pichardo J."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/name"Bioorg. Med. Chem. Lett."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/name"Bioorg Med Chem Lett"xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/pages"4475-4478"xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/pages"4475-4478"xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/title"Synthesis and biological activity of macrocyclic inhibitors of hepatitis C virus (HCV) NS3 protease."xsd:string
http://purl.uniprot.org/citations/16112859http://purl.uniprot.org/core/title"Synthesis and biological activity of macrocyclic inhibitors of hepatitis C virus (HCV) NS3 protease."xsd:string