| http://purl.uniprot.org/citations/16126250 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16126250 | http://www.w3.org/2000/01/rdf-schema#comment | "There is currently of a great interest investigating the role of nutrition in the prevention of age-associated disorders. The present study aimed to evaluate, on a particular strain of mice, the efficacy of alternate-day fasting on the mitochondrial production of free radical species and on the incidence of a specific cancer (lymphoma) in aged mice. Alternate fasting, that was initiated in middle age mice through a 4 month period, reduced significantly the incidence of lymphoma (0% versus 33% for controls). No remarkable difference was observed in the overall food consumption between alternate-fed (AF) and ad libitum (AL) mice, suggesting that the efficacy of alternate fasting did not really depend on calorie restriction. A significant decrease in the mitochondrial generation of reactive oxygen species (ROS) that was associated with a significant increase in spleen mitochondria SOD activity was observed when mice were maintained on intermittent fasting. Our results suggest that alternate fasting could exert a beneficial antioxidant effect and a modulation of the oxidative stress associated with aging."xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.mad.2005.06.007"xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/author | "Ducros V."xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/author | "Descamps O."xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/author | "Riondel J."xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/author | "Roussel A.M."xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/name | "Mech Ageing Dev"xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/pages | "1185-1191"xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/title | "Mitochondrial production of reactive oxygen species and incidence of age-associated lymphoma in OF1 mice: effect of alternate-day fasting."xsd:string |
| http://purl.uniprot.org/citations/16126250 | http://purl.uniprot.org/core/volume | "126"xsd:string |
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