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http://purl.uniprot.org/citations/16133451http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16133451http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16133451http://www.w3.org/2000/01/rdf-schema#comment"Mammals have several major histocompatibility complex (MHC) class-I-like genes. Although some of them are assumed to have originated before the emergence of mammals, the origin of class-I-like genes is poorly understood. We analyzed here the recently released chicken draft genome sequence and identified two families of class-I-like genes: CD1 and PROCR (the gene for the endothelial protein C receptor). Chickens have two CD1 genes, designated CD1.1 and CD1.2, located in tandem approximately 840 bp apart from each other. Chicken CD1.1 and CD1.2 are neither group 1-nor group 2-like, indicating that the two groups of CD1 emerged in a mammalian lineage. Although the database provides no information as to their chromosomal localization, we found that chicken CD1 genes are located adjacent to the previously characterized MHC B system contig on chromosome 16. We confirmed the linkage of CD1 to the B system by dual-color fluorescence in situ hybridization. Chickens have a single copy of PROCR. Among known class-I-like genes, PROCR is most closely related to CD1, indicating that CD1 and PROCR constitute a distinct subfamily of class-I-like genes that predates the emergence of mammals."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.org/dc/terms/identifier"doi:10.1007/s00251-005-0016-y"xsd:string
http://purl.uniprot.org/citations/16133451http://purl.org/dc/terms/identifier"doi:10.1007/s00251-005-0016-y"xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Tanabe H."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Tanabe H."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Kasahara M."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Kasahara M."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Chiba M."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Chiba M."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Maruoka T."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/author"Maruoka T."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/name"Immunogenetics"xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/name"Immunogenetics"xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/pages"590-600"xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/pages"590-600"xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/title"Chicken CD1 genes are located in the MHC: CD1 and endothelial protein C receptor genes constitute a distinct subfamily of class-I-like genes that predates the emergence of mammals."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/title"Chicken CD1 genes are located in the MHC: CD1 and endothelial protein C receptor genes constitute a distinct subfamily of class-I-like genes that predates the emergence of mammals."xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/volume"57"xsd:string
http://purl.uniprot.org/citations/16133451http://purl.uniprot.org/core/volume"57"xsd:string
http://purl.uniprot.org/citations/16133451http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16133451
http://purl.uniprot.org/citations/16133451http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16133451