| http://purl.uniprot.org/citations/16140982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16140982 | http://www.w3.org/2000/01/rdf-schema#comment | "Microphthalmia-associated transcription factor (MITF) M-form is a melanocyte-specific transcription factor that plays a key role in melanocyte development, survival, and differentiation. Here, we identified MITF as a new substrate of caspases and we characterized the cleavage site after Asp 345 in the C-terminal domain. We show that expression of a noncleavable form of MITF renders melanoma cells resistant to apoptotic stimuli, and we found that the C-terminal fragment generated upon caspase cleavage is endowed with a proapoptotic activity that sensitizes melanoma cells to death signals. The proapoptotic function gained by MITF following its processing by caspases provides a tissue-restricted means to modulate death in melanocyte and melanoma cells."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.335905"xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Auberger P."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Ballotti R."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Ortonne J.P."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Bertolotto C."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Bille K."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Khaled M."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Larribere L."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Gaggioli C."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/author | "Hilmi C."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/pages | "1980-1985"xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/title | "The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis."xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://purl.uniprot.org/core/volume | "19"xsd:string |
| http://purl.uniprot.org/citations/16140982 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16140982 |
| http://purl.uniprot.org/citations/16140982 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16140982 |
| http://purl.uniprot.org/uniprot/#_A0A087WXU1-mappedCitation-16140982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16140982 |
| http://purl.uniprot.org/uniprot/#_A0A0H3W5T2-mappedCitation-16140982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16140982 |
| http://purl.uniprot.org/uniprot/#_A0A8F9W6H4-mappedCitation-16140982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16140982 |
| http://purl.uniprot.org/uniprot/#_A0A0A7NWS7-mappedCitation-16140982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16140982 |
| http://purl.uniprot.org/uniprot/#_B4DNC7-mappedCitation-16140982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16140982 |
| http://purl.uniprot.org/uniprot/#_A8K5K3-mappedCitation-16140982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16140982 |