http://purl.uniprot.org/citations/16166642 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16166642 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16166642 | http://www.w3.org/2000/01/rdf-schema#comment | "We report the identification and characterization of JAMP (JNK1 [Jun N-terminal kinase 1]-associated membrane protein), a predicted seven-transmembrane protein that is localized primarily within the plasma membrane and associates with JNK1 through its C-terminal domain. JAMP association with JNK1 outcompetes JNK1 association with mitogen-activated protein kinase phosphatase 5, resulting in increased and prolonged JNK1 activity following stress. Elevated expression of JAMP following UV or tunicamycin treatment results in sustained JNK activity and a higher level of JNK-dependent apoptosis. Inhibition of JAMP expression by RNA interference reduces the degree and duration of JNK activation and concomitantly the level of stress-induced apoptosis. Through its regulation of JNK1 activity, JAMP emerges as a membrane-anchored regulator of the duration of JNK1 activity in response to diverse stress stimuli."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.25.19.8619-8630.2005"xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.25.19.8619-8630.2005"xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Asahara T."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Asahara T."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Bhoumik A."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Bhoumik A."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Ronai Z."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Ronai Z."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Broday L."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Broday L."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Tcherpakov M."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Tcherpakov M."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Bromberg K.D."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Bromberg K.D."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Didier C."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Didier C."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Kadoya T."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Kadoya T."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Khurana A."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/author | "Khurana A."xsd:string |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16166642 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |