http://purl.uniprot.org/citations/16169296 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16169296 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16169296 | http://www.w3.org/2000/01/rdf-schema#comment | "Cytochrome b561 family was characterized by the presence of "b561 core domain" that forms a transmembrane four helix bundle containing four totally conserved His residues, which might coordinate two heme b groups. We conducted BLAST and PSI-BLAST searches to obtain insights on structure and functions of this protein family. Analyses with CLUSTAL W on b561 sequences from various organisms showed that the members could be classified into 7 subfamilies based on characteristic motifs; groups A (animals/neuroendocrine), B (plants), C (insects), D (fungi), E (animals/TSF), F (plants+DoH), and G (SDR2). In group A, both motif 1, {FN(X)HP(X)2M(X)2G(X)5G(X)ALLVYR}, and motif 2, {YSLHSW(X)G}, were identified. These two motifs were also conserved in group B. There was no significant features characteristic to groups C and D. A modified version of motif 1, {LFSWHP(X)2M(X)3F(X)3M(X)EAIL(X)SP(X)2SS}, was found in group E with a high degree of conservation. Both motif 3, {DP(X)WFY(L)H(X)3Q}, and motif 4, {K(X)R(X)YWN(X)YHH(X)2G(R/Y)} ,were found in group F at different regions from those of motifs 1 and 2. The "DoH" domain common to the NH2-terminal region of dopamine beta-hydroxylase was found to form fusion proteins with the b561 core domains in groups F and G. Based on these results, we proposed a hypothesis regarding structures and functions of the 7 subfamilies of cytochrome b561."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbapap.2005.08.015"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbapap.2005.08.015"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/author | "Takeuchi F."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/author | "Takeuchi F."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/author | "Nakanishi N."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/author | "Nakanishi N."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/author | "Tsubaki M."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/author | "Tsubaki M."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/name | "Biochim. Biophys. Acta"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/name | "Biochim. Biophys. Acta"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/pages | "174-190"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/pages | "174-190"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/title | "Cytochrome b561 protein family: expanding roles and versatile transmembrane electron transfer abilities as predicted by a new classification system and protein sequence motif analyses."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/title | "Cytochrome b561 protein family: expanding roles and versatile transmembrane electron transfer abilities as predicted by a new classification system and protein sequence motif analyses."xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/volume | "1753"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://purl.uniprot.org/core/volume | "1753"xsd:string |
http://purl.uniprot.org/citations/16169296 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16169296 |
http://purl.uniprot.org/citations/16169296 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16169296 |
http://purl.uniprot.org/citations/16169296 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16169296 |
http://purl.uniprot.org/citations/16169296 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16169296 |