| http://purl.uniprot.org/citations/16183092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16183092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16183092 | http://www.w3.org/2000/01/rdf-schema#comment | "Two peptide toxins, acrorhagin I (50 residues) and II (44 residues), were isolated from special aggressive organs (acrorhagi) of the sea anemone Actinia equina by gel filtration on Sephadex G-50 and reverse-phase HPLC on TSKgel ODS-120T. The LD50 against crabs of acrorhagin I and II were estimated to be 520 and 80 microg/kg, respectively. 3'- and 5'-RACE established the amino acid sequences of the acrorhagin precursors. The precursor of acrorhagin I is composed of both signal and mature peptides and that of acrorhagin II has an additional sequence (propart) between signal and mature peptides. Acrorhagin I has no sequence homologies with any toxins, while acrorhagin II is somewhat similar to spider neurotoxins (hainantoxin-I from Selenocosmia hainana and Tx 3-2 from Phoneutria nigriventer) and cone snail neurotoxin (omega-conotoxin MVIIB from Conus magus). In addition, analogous peptides (acrorhagin Ia and IIa) were also cloned during RT-PCR experiments performed to confirm the nucleotide sequences of acrorhagins. This is the first to demonstrate the existence of novel peptide toxins in the sea anemone acrorhagi."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.toxicon.2005.08.003"xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.toxicon.2005.08.003"xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Ishida M."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Ishida M."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Nagashima Y."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Nagashima Y."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Shiomi K."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Shiomi K."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Honma T."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Honma T."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Nagai H."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Nagai H."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Minagawa S."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/author | "Minagawa S."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/name | "Toxicon"xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/name | "Toxicon"xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/pages | "768-774"xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/pages | "768-774"xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/title | "Novel peptide toxins from acrorhagi, aggressive organs of the sea anemone Actinia equina."xsd:string |
| http://purl.uniprot.org/citations/16183092 | http://purl.uniprot.org/core/title | "Novel peptide toxins from acrorhagi, aggressive organs of the sea anemone Actinia equina."xsd:string |