| http://purl.uniprot.org/citations/16186110 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16186110 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16186110 | http://www.w3.org/2000/01/rdf-schema#comment | "Saitohin is a gene unique to humans and their closest relatives, the function of which is not yet known. Saitohin contains a single polymorphism (Q7R), and its Q and R alleles belong to the H1 and H2 tau haplotype, respectively. The Saitohin Q allele confers susceptibility to several neurodegenerative diseases. To get a handle on Saitohin function, we used it as a bait in a yeast two-hybrid screen. By this assay and subsequent co-immunoprecipitation and glutathione S-transferase pull-down assays, we discovered and confirmed that Saitohin interacts with peroxiredoxin 6, a unique member of that family that is bifunctional and the levels of which increase in Pick disease. The strength of the interaction appeared to be allele-specific, giving the first distinction between the two forms of Saitohin."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m506116200"xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m506116200"xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Gao L."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Gao L."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Conrad C."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Conrad C."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Andreadis A."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Andreadis A."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Tse S.-W."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/author | "Tse S.-W."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/pages | "39268-39272"xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/pages | "39268-39272"xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/title | "Saitohin, which is nested in the tau locus and confers allele-specific susceptibility to several neurodegenerative diseases, interacts with peroxiredoxin 6."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/title | "Saitohin, which is nested in the tau locus and confers allele-specific susceptibility to several neurodegenerative diseases, interacts with peroxiredoxin 6."xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/volume | "280"xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://purl.uniprot.org/core/volume | "280"xsd:string |
| http://purl.uniprot.org/citations/16186110 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16186110 |
| http://purl.uniprot.org/citations/16186110 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16186110 |