http://purl.uniprot.org/citations/16203048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16203048 | http://www.w3.org/2000/01/rdf-schema#comment | "MUC7 is a low molecular weight monomeric mucin secreted by submandibular, sublingual and minor salivary glands. This mucin has been implicated in the non-immune host defense system in the oral cavity since it binds and agglutinates a variety of oral microbes. To investigate interactions between this mucin and other secretory salivary proteins, a submandibular gland prey library was screened with baits encoding the N- and C-terminal regions of MUC7 in the yeast two-hybrid system. The N-terminal region interacted with several secretory salivary proteins, whereas the C-terminal region did not. Interacting proteins included amylase, acidic proline-rich protein 2, basic proline-rich protein 3, lacrimal proline-rich protein 4, statherin and histatin 1. Formation of complexes between these proteins and the N-terminal region of MUC7 was confirmed in Far Western blotting experiments. Interactions between mucin and non-mucin proteins in saliva could protect complex partners from proteolysis, modulate the biological activity of complexed proteins or serve as a delivery system for distribution of secretory salivary proteins throughout the oral cavity."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbamcr.2005.08.007"xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Offner G.D."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Troxler R.F."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Wang L."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Oppenheim F.G."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Siqueira C.C."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Bruno L.S."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/author | "Soares R.V."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/pages | "65-72"xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/title | "Two-hybrid analysis of human salivary mucin MUC7 interactions."xsd:string |
http://purl.uniprot.org/citations/16203048 | http://purl.uniprot.org/core/volume | "1746"xsd:string |
http://purl.uniprot.org/citations/16203048 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16203048 |
http://purl.uniprot.org/citations/16203048 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16203048 |
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