RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16203048http://www.w3.org/2000/01/rdf-schema#comment"MUC7 is a low molecular weight monomeric mucin secreted by submandibular, sublingual and minor salivary glands. This mucin has been implicated in the non-immune host defense system in the oral cavity since it binds and agglutinates a variety of oral microbes. To investigate interactions between this mucin and other secretory salivary proteins, a submandibular gland prey library was screened with baits encoding the N- and C-terminal regions of MUC7 in the yeast two-hybrid system. The N-terminal region interacted with several secretory salivary proteins, whereas the C-terminal region did not. Interacting proteins included amylase, acidic proline-rich protein 2, basic proline-rich protein 3, lacrimal proline-rich protein 4, statherin and histatin 1. Formation of complexes between these proteins and the N-terminal region of MUC7 was confirmed in Far Western blotting experiments. Interactions between mucin and non-mucin proteins in saliva could protect complex partners from proteolysis, modulate the biological activity of complexed proteins or serve as a delivery system for distribution of secretory salivary proteins throughout the oral cavity."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.org/dc/terms/identifier"doi:10.1016/j.bbamcr.2005.08.007"xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Li X."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Offner G.D."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Troxler R.F."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Wang L."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Oppenheim F.G."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Siqueira C.C."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Bruno L.S."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/author"Soares R.V."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/name"Biochim Biophys Acta"xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/pages"65-72"xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/title"Two-hybrid analysis of human salivary mucin MUC7 interactions."xsd:string
http://purl.uniprot.org/citations/16203048http://purl.uniprot.org/core/volume"1746"xsd:string
http://purl.uniprot.org/citations/16203048http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16203048
http://purl.uniprot.org/citations/16203048http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16203048
http://purl.uniprot.org/uniprot/#_O15230-mappedCitation-16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16203048
http://purl.uniprot.org/uniprot/#_P15515-mappedCitation-16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16203048
http://purl.uniprot.org/uniprot/#_P15516-mappedCitation-16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16203048
http://purl.uniprot.org/uniprot/#_P02808-mappedCitation-16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16203048
http://purl.uniprot.org/uniprot/#_P02810-mappedCitation-16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16203048
http://purl.uniprot.org/uniprot/#_P02814-mappedCitation-16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16203048
http://purl.uniprot.org/uniprot/#_P30048-mappedCitation-16203048http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16203048