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http://purl.uniprot.org/citations/16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16225776http://www.w3.org/2000/01/rdf-schema#comment"Autoimmune mechanisms are likely involved in the pathogenesis of idiopathic dilated cardiomyopathy (IDC) and components of MHC may serve as markers for the propensity to develop immune-mediated myocardial damage. This study was conducted to investigate the possible association between HLA-DQA1, -DQB1 alleles and IDC in Han population from northern China by using PCR-based sequence-specific primer (PCR-SSP) technique for HLA genotyping. Among 68 unrelated IDC patients, 4 probands of IDC pedigrees and 100 healthy controls, we found that the alleles of HLA-DQA1*0501 and HLA-DQB1*0303 conferred susceptibility to IDC while HLA-DQA1*0201 and HLA-DQB1*0502, *0504 alleles were in negative association with IDC. The serine at position 57 (SER57) in the exon of HLA-DQB1*0502 and *0504 was confirmed in our experiment as a marker for resistance to IDC. The results suggest that HLA-DQ polymorphism may be involved in the pathogenesis of IDC."xsd:string
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/author"Li W."xsd:string
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/author"Liu W."xsd:string
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/author"Sun N."xsd:string
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/name"Cell Mol Immunol"xsd:string
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/pages"311-314"xsd:string
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/title"Association of HLA-DQ with idiopathic dilated cardiomyopathy in a northern Chinese Han population."xsd:string
http://purl.uniprot.org/citations/16225776http://purl.uniprot.org/core/volume"1"xsd:string
http://purl.uniprot.org/citations/16225776http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16225776
http://purl.uniprot.org/citations/16225776http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16225776
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A076L4M5-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0A7C7I5-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0A7C853-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0A7CAC7-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0A7CAE0-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0A7CAE6-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0E3DCZ4-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0E3DCZ9-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0E3DD03-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0E3DD05-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776
http://purl.uniprot.org/uniprot/#_A0A0E3DD07-mappedCitation-16225776http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16225776