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http://purl.uniprot.org/citations/16228003http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16228003http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16228003http://www.w3.org/2000/01/rdf-schema#comment"As a counter-defense against antiviral RNA silencing during infection, the insect Flock House virus (FHV) expresses the silencing suppressor protein B2. Biochemical experiments show that B2 binds to double-stranded RNA (dsRNA) without regard to length and inhibits cleavage of dsRNA by Dicer in vitro. A cocrystal structure reveals that a B2 dimer forms a four-helix bundle that binds to one face of an A-form RNA duplex independently of sequence. These results suggest that B2 blocks both cleavage of the FHV genome by Dicer and incorporation of FHV small interfering RNAs into the RNA-induced silencing complex."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.org/dc/terms/identifier"doi:10.1038/nsmb1005"xsd:string
http://purl.uniprot.org/citations/16228003http://purl.org/dc/terms/identifier"doi:10.1038/nsmb1005"xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Chao J.A."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Chao J.A."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Lee J.H."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Lee J.H."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Chapados B.R."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Chapados B.R."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Debler E.W."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Debler E.W."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Schneemann A."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Schneemann A."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Williamson J.R."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/author"Williamson J.R."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/pages"952-957"xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/pages"952-957"xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/title"Dual modes of RNA-silencing suppression by Flock House virus protein B2."xsd:string
http://purl.uniprot.org/citations/16228003http://purl.uniprot.org/core/title"Dual modes of RNA-silencing suppression by Flock House virus protein B2."xsd:string