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http://purl.uniprot.org/citations/16250632 | http://www.w3.org/2000/01/rdf-schema#comment | "Design, synthesis, and biological evaluation of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease (SARS-3CLpro) inhibitors for severe acute respiratory syndrome coronavirus (SARS-CoV) are described. These inhibitors exhibited antiviral activity against SARS-CoV in infected cells in the micromolar range. An X-ray crystal structure of our lead inhibitor (4) bound to SARS-3CLpro provided important drug-design templates for the design of small-molecule inhibitors."xsd:string |
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http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Rota P.A."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Ghosh A.K."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Baker S.C."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Fu W."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Harcourt B.H."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Santarsiero B.D."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Mesecar A.D."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Ratia K."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Johnson M.E."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/author | "Xi K."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/name | "J Med Chem"xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/pages | "6767-6771"xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/title | "Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors."xsd:string |
http://purl.uniprot.org/citations/16250632 | http://purl.uniprot.org/core/volume | "48"xsd:string |
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