http://purl.uniprot.org/citations/16263078 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16263078 | http://www.w3.org/2000/01/rdf-schema#comment | "Infection of SARS-associated coronavirus (SARS-CoV) induced a strong anti-nucleocapsid (anti-N) antibody response. However, the pathophysiological significance of the anti-N antibodies in SARS pathogenesis is largely unknown. To profile the anti-N antibodies, a phage-displayed scFv library was prepared from mice immunized with heat-inactivated SARS-CoV-infected Vero E6 cell lysate. Specific anti-N scFvs were isolated by panning against a recombinant nucleocapsid protein and reactivity was confirmed with phage-ELISA. Sequence analysis indicated that two of the isolated anti-N scFv clones were identical and displayed a high homology with an scFv specific for interleukin 11 (IL-11), an anti-inflammatory cytokine derived from bone marrow stroma cells. In a neutralization assay, IL-11-induced STAT 3 phosphorylation in rat intestinal epithelial IEC-18 cells was completely suppressed by the anti-N scFv clone L9N01."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2005.10.088"xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Lee S.S."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Cheng M."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Chan C.W."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Chan P.K."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Zhao Q."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Au S.W."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Cheng G."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Cheung W.T."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Bikkavilli R.K."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Ho W.K."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/author | "Cheung R.C."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/pages | "1654-1660"xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/title | "Cross-reactivity of antibody against SARS-coronavirus nucleocapsid protein with IL-11."xsd:string |
http://purl.uniprot.org/citations/16263078 | http://purl.uniprot.org/core/volume | "338"xsd:string |
http://purl.uniprot.org/citations/16263078 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16263078 |
http://purl.uniprot.org/citations/16263078 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16263078 |
http://purl.uniprot.org/uniprot/#_P52631-mappedCitation-16263078 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16263078 |
http://purl.uniprot.org/uniprot/P52631 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16263078 |