| http://purl.uniprot.org/citations/16287978 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16287978 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16287978 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16287978 | http://www.w3.org/2000/01/rdf-schema#comment | "Botulinum neurotoxins (BoNTXs) produced by Clostridium botulinum are among the most poisonous substances known. Of the seven types of BoNTXs, genes for type C1 and D toxins (BoNTX/C1 and D) are carried by bacteriophages. The gene for exoenzyme C3 also resides on these phages. Here, we present the complete genome sequence of c-st, a representative of BoNTX/C1-converting phages. The genome is a linear double-stranded DNA of 185,682 bp with 404-bp terminal direct repeats, the largest known temperate phage genome. We identified 198 potential protein-coding regions, including the genes for production of BoNTX/C1 and exoenzyme C3. Very exceptionally, as a viable bacteriophage, a number of insertion sequences were found on the c-st genome. By analyzing the molecular structure of the c-st genome in lysogens, we also found that it exists as a circular plasmid prophage. These features account for the unstable lysogeny of BoNTX phages, which has historically been called "pseudolysogeny." The PCR scanning analysis of other BoNTX/C1 and D phages based on the c-st sequence further revealed that BoNTX phages comprise a divergent phage family, probably generated by exchanging genomic segments among BoNTX phages and their relatives."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0505503102"xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0505503102"xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0505503102"xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16287978 |
| http://purl.uniprot.org/citations/16287978 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16287978 |
| http://purl.uniprot.org/citations/16287978 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16287978 |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Hayashi T."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Hayashi T."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Hayashi T."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Hattori M."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Hattori M."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Hattori M."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Nakayama K."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Nakayama K."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Nakayama K."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Ohnishi M."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Ohnishi M."xsd:string |
| http://purl.uniprot.org/citations/16287978 | http://purl.uniprot.org/core/author | "Ohnishi M."xsd:string |