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http://purl.uniprot.org/citations/16359841http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16359841http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16359841http://www.w3.org/2000/01/rdf-schema#comment"In an initial study, we compared quantitative transcriptome data across mouse brain territories using the serial analysis of gene expression method. Among the novel regional markers that we discovered, we focused on a striatum-enriched transcript with no available experimental cDNA sequence. Here, we report its cloning, gene structure, and detailed distribution in mouse brain. Quantitative RT-PCR and in situ hybridization demonstrated predominant expression in dorsolateral striatum. We therefore named it capucin for caudate-and putamen-enriched sequence. Mouse capucin is a 237-amino-acid protein, without any registered ortholog in mammalian species. It contains no recognizable motif other than two predicted carboxy-terminal transmembrane domains. When expressed in fusion with a fluorescent protein, it localized to the Golgi apparatus in two mammalian cell lines. Interestingly, we observed a significant down-regulation of capucin mRNA levels in two rodent models of Huntington disease, indicating a possible contribution to the pathogenesis of this disorder."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.org/dc/terms/identifier"doi:10.1016/j.ygeno.2005.10.009"xsd:string
http://purl.uniprot.org/citations/16359841http://purl.org/dc/terms/identifier"doi:10.1016/j.ygeno.2005.10.009"xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Brochier C."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Brochier C."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Elalouf J.-M."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Elalouf J.-M."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Luthi-Carter R."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Luthi-Carter R."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Gaillard M.-C."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Gaillard M.-C."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Caudy N."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Caudy N."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Van de Vel A."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"Van de Vel A."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"de Chaldee M."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/author"de Chaldee M."xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/pages"200-207"xsd:string
http://purl.uniprot.org/citations/16359841http://purl.uniprot.org/core/pages"200-207"xsd:string