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http://purl.uniprot.org/citations/16375118http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16375118http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To study the expression of vascular endothelial growth factor (VEGF) and both the Flt-1 and KDR high affinity VEGF receptors in human laryngeal carcinoma cells and its significance.

Method

In this study, we investigated the expression of VEGF mRNA and both the Fit-1 mRNA and KDR mRNA high affinity VEGF receptors in human laryngeal carcinoma cells using techniques of semi-quantify RT-PCR.

Result

It was showed that the expression level of VEGF mRNA was significantly increased in human laryngeal carcinoma cells as compared with the normal cells, Hacat cells (P <0.05), and there was the high expression level of Flt-1 mRNA in the Hep-2 cells, but not KDR mRNA.

Conclusion

These data raise the possibility that VEGF and its receptors many play key roles in the growth, invasion and metastasis of human laryngeal carcinoma cells through either a paracrine or an autocrine mechanism."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Chen P."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Ding J."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Chen G."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Fu Y."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Liu Y."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Luo L."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Song P."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Gong S."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/author"Yan K."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/name"Lin Chuang Er Bi Yan Hou Ke Za Zhi"xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/pages"842-844"xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/title"[Expression of vascular endothelial growth factor and its receptors in laryngeal carcinoma cell and its significance]."xsd:string
http://purl.uniprot.org/citations/16375118http://purl.uniprot.org/core/volume"19"xsd:string
http://purl.uniprot.org/citations/16375118http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16375118
http://purl.uniprot.org/citations/16375118http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16375118
http://purl.uniprot.org/uniprot/#_A0A0U2WZU8-mappedCitation-16375118http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16375118
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http://purl.uniprot.org/uniprot/#_A0A0H4A7S0-mappedCitation-16375118http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16375118
http://purl.uniprot.org/uniprot/#_A0A0H4A7S4-mappedCitation-16375118http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16375118
http://purl.uniprot.org/uniprot/#_A0A0H4ADZ1-mappedCitation-16375118http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16375118
http://purl.uniprot.org/uniprot/#_A0A0H4AF76-mappedCitation-16375118http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16375118
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