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http://purl.uniprot.org/citations/16376304http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16376304http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16376304http://www.w3.org/2000/01/rdf-schema#comment"We have identified a new human gene coined sytdep (synaptotagmin XIV-derived protein) in human neutrophils. Sytdep encodes a 188-amino acid sequence with a 21.435kDa deduced molecular mass, showing 75% identity to human synaptotagmin (syt) XIV. Human neutrophils express sytdep, but not syt XIV. Sytdep was upregulated during HL-60 neutrophil differentiation. Sytdep gene is located in human chromosome 4 and contains a unique exon, whereas syt XIV gene, located in chromosome 1, comprises 10 exons with 9 introns. Mouse genome did not contain sytdep. The N-terminal region of sytdep shows no homology with any known protein and, unlike synaptotagmin XIV isoforms, sytdep shows a unique C-terminal C2B domain. Polyclonal antibodies against the C2B domain of syt XIV recognized sytdep as a 27-kDa protein in human neutrophils. Genomic analyses suggest that human sytdep could derive from a retrotranslocation of a syt XIV transcript into chromosome 4."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2005.11.184"xsd:string
http://purl.uniprot.org/citations/16376304http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2005.11.184"xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/author"Fukuda M."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/author"Fukuda M."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/author"Mollinedo F."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/author"Mollinedo F."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/author"Herrero-Turrion M.J."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/author"Herrero-Turrion M.J."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/pages"386-394"xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/pages"386-394"xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/title"Cloning and genomic characterization of sytdep, a new synaptotagmin XIV-related gene."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/title"Cloning and genomic characterization of sytdep, a new synaptotagmin XIV-related gene."xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/volume"340"xsd:string
http://purl.uniprot.org/citations/16376304http://purl.uniprot.org/core/volume"340"xsd:string
http://purl.uniprot.org/citations/16376304http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16376304
http://purl.uniprot.org/citations/16376304http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16376304
http://purl.uniprot.org/citations/16376304http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16376304
http://purl.uniprot.org/citations/16376304http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16376304