| http://purl.uniprot.org/citations/16376427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16376427 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16376427 | http://www.w3.org/2000/01/rdf-schema#comment | "Cyclosporin-A and FK506 block the calcineurin activity preventing the transcription of genes sharing NFAT-like binding sequences in their promoter region. We presently show that activation of murine T-cells in presence of these immunosuppressors results in the up-regulation of the synaptotagmin-like 2 gene. However, of the four known isoforms, only mRNAs encoding the a and b isoforms accumulate. Two previously undected isoforms, each characterized by the retention of an intron, were found. The first, Slp2-e, includes exon 8, intron 8 and exon 9. The second, Slp2-f, is composed of exon 7, intron 7 and exon 8. Slp2-f has an open reading frame coding for a putative protein of 1229 amino acids sharing 47% identities with the human breast-associated antigen, SGA-72 M. In addition to the well-documented modulation of gene transcription, the two immunosuppressors also play a role in the choice of alternative splice sites on murine Slp2 pre-mRNA."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2005.10.019"xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2005.10.019"xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Truffa-Bachi P."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Truffa-Bachi P."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Mascarell L."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Mascarell L."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Auger R."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Auger R."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Kanellopoulos J.M."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/author | "Kanellopoulos J.M."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/name | "Mol. Immunol."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/name | "Mol. Immunol."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/pages | "1846-1854"xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/pages | "1846-1854"xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/title | "The usage of alternative splice sites in Mus musculus synaptotagmin-like 2 gene is modulated by cyclosporin A and FK506 in T-lymphocytes."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/title | "The usage of alternative splice sites in Mus musculus synaptotagmin-like 2 gene is modulated by cyclosporin A and FK506 in T-lymphocytes."xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/volume | "43"xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://purl.uniprot.org/core/volume | "43"xsd:string |
| http://purl.uniprot.org/citations/16376427 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16376427 |
| http://purl.uniprot.org/citations/16376427 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16376427 |