| http://purl.uniprot.org/citations/16378758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16378758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16378758 | http://www.w3.org/2000/01/rdf-schema#comment | "Fibroblast growth factor 2 (FGF2) plays an important role in cortical development. However, the genes downstream of FGF2 that mediate its effect are largely unknown. We have performed a microarray screening of genes regulated by FGF2 using primary cortical neuron culture derived from embryonic day 14.5 (E14.5) mouse forebrains. In this study, we have analysed a previously uncharacterised gene encoding a 180-amino acid protein, hereby named 'coiled-coil protein 1 (ccp1)', that showed a modest up-regulation upon FGF2 stimulation. Northern blots and RT-PCR showed specific expression of ccp1 in multiple tissues including adult and embryonic brains. In situ hybridizations revealed that ccp1 was expressed in the cortical plate between Reelin and Tbr1-positive layers in the dorsal cortex at E15.5. Furthermore, the expression pattern of ccp1 at E13.5-E14.5 reflected some of the aspects of tangential migration of cortical progenitors during the early phase. We observed that the expressed ccp1 protein was localised to endo/lysosomal compartment in the cell body as well as to vesicles present in the processes of primary cortical neurons and oligodendrocyte cell line."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.modgep.2005.07.004"xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.modgep.2005.07.004"xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Ansorge W."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Ansorge W."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Iwata T."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Iwata T."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Inglis-Broadgate S.L."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Inglis-Broadgate S.L."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Pante G."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Pante G."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Pellicano F."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/author | "Pellicano F."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/name | "Gene Expr. Patterns"xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/name | "Gene Expr. Patterns"xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/pages | "285-293"xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/pages | "285-293"xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/title | "Expression of coiled-coil protein 1, a novel gene downstream of FGF2, in the developing brain."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/title | "Expression of coiled-coil protein 1, a novel gene downstream of FGF2, in the developing brain."xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/16378758 | http://purl.uniprot.org/core/volume | "6"xsd:string |