| http://purl.uniprot.org/citations/16391516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16391516 | http://www.w3.org/2000/01/rdf-schema#comment | "The eotaxin gene family (eotaxin, eotaxin-2 and eotaxin-3) have been implicated in the recruitment of eosinophils, basophiles and helper T (Th) 2 lymphocytes that is a central aspect of allergic disease. We previously suggested that Eo2+179T>C and Eo2 +275C>T of the eotaxin-2, and Eo3 +2497T>G of the eotaxin-3 were significantly associated with susceptibility to asthma. To determine whether the single nucleotide polymorphisms (SNPs) of eotaxin-2 and eotaxin-3 gene family are associated with the susceptibility of ulcerative colitis (UC), we analyzed the genotype of 119 patients with UC and 303 controls using single-base extension (SBE) method. We also calculated the haplotype frequencies among Eo2 +179T>C and Eo2 +275C >T of the eotaxin-2 and Eo3 +2497T>G of the eotaxin-3 in both control and UC patients. The genotype frequency of Eo2 +179T>C and Eo2 +275C>T between UC patients and controls were significantly different (P=0.006 and 0.022, respectively). The genotype and allele frequencies of EoA2497T>G in UC patients were not significantly different from those in the controls without UC patients. Our results suggest that Eo2 +179T>C and Eo2 +275C>T of eotaxin-2 might be associated with the susceptibility of UC."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.org/dc/terms/identifier | "doi:10.1038/emm.2005.68"xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/author | "Kim K.S."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/author | "Chae S.C."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/author | "Lee S.T."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/author | "Choi S.C."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/author | "Park Y.R."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/author | "Chung H.T."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/name | "Exp Mol Med"xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/pages | "553-558"xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/title | "The association of eotaxin-2 and eotaxin-3 gene polymorphisms in a Korean population with ulcerative colitis."xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/16391516 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16391516 |
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