| http://purl.uniprot.org/citations/16408249 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16408249 | http://www.w3.org/2000/01/rdf-schema#comment | "The rodent preputial gland secretes aggression-promoting pheromones and expresses melanocortin-5 receptor (MC5R), but the functional relationship is poorly understood. We investigated whether MC5R deficiency in male mice alters stimulatory melanocortin influences on preputial growth and pheromone-induced aggression. In wild-type (MC5R(+/+)) pairs, repeated NDP-MSH injection decreased attack latency and increased aggression in initial attackers. Similar NDP-MSH treatment in MC5R-deficient (MC5R(-/-)) pairs failed to alter attack latency or aggression frequency, but aggression increased in vehicle-injected opponents. NDP-MSH treatment promoted preputial hypertrophy, and in MC5R(+/+) mice paired against non-aggressive stimulus opponents it decreased attack latency and increased aggression. MC5R(-/-) mice were insensitive to behavioral and physiological effects of NDP-MSH, and preputialectomized mice were insensitive to behavioral effects of NDP-MSH. The results suggest that MC5R inactivation reduced a pheromonal signal for aggression that acts on donors, rather than their opponents."xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10519-005-9024-9"xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://purl.uniprot.org/core/author | "Morgan C."xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://purl.uniprot.org/core/author | "Cone R.D."xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16408249 | http://purl.uniprot.org/core/name | "Behav Genet"xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://purl.uniprot.org/core/pages | "291-300"xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://purl.uniprot.org/core/title | "Melanocortin-5 receptor deficiency in mice blocks a novel pathway influencing pheromone-induced aggression."xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://purl.uniprot.org/core/volume | "36"xsd:string |
| http://purl.uniprot.org/citations/16408249 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16408249 |
| http://purl.uniprot.org/citations/16408249 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16408249 |
| http://purl.uniprot.org/uniprot/#_G3UWB6-mappedCitation-16408249 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16408249 |
| http://purl.uniprot.org/uniprot/#_P41149-mappedCitation-16408249 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16408249 |
| http://purl.uniprot.org/uniprot/#_Q496T0-mappedCitation-16408249 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16408249 |
| http://purl.uniprot.org/uniprot/P41149 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16408249 |
| http://purl.uniprot.org/uniprot/Q496T0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16408249 |
| http://purl.uniprot.org/uniprot/G3UWB6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16408249 |