| http://purl.uniprot.org/citations/16428424 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16428424 | http://www.w3.org/2000/01/rdf-schema#comment | "An Escherichia coli mutant was isolated and shown to be polymyxin B resistant. Mapping and sequence analysis revealed a missense mutation at codon 53 within the pmrA (basR) gene that results in a G-to-V substitution. Fusions of promoters from the pmrC, yibD, and pmrH genes with the lacZ reporter showed that they were constitutively expressed in pmrA53 cells. In pmrA+ strains, these promoters were induced by iron and zinc, while a DeltapmrA mutation blocked induction. The PmrA regulon regulates genes whose products remodel the composition and charge of lipid A and hence the barrier properties of the outer membrane. Along these lines, the pmrA53 mutant was also found to be hypersensitive to the anionic bile detergent deoxycholic acid."xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.188.3.1180-1183.2006"xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/author | "Tran K."xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/author | "Wall D."xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/author | "Froelich J.M."xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/name | "J Bacteriol"xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/pages | "1180-1183"xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/title | "A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid."xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://purl.uniprot.org/core/volume | "188"xsd:string |
| http://purl.uniprot.org/citations/16428424 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16428424 |
| http://purl.uniprot.org/citations/16428424 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16428424 |
| http://purl.uniprot.org/uniprot/P30843#attribution-EEADB4C7E079573A33210715C3DD4E53 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16428424 |
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| http://purl.uniprot.org/uniprot/P11290 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16428424 |