http://purl.uniprot.org/citations/16430890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16430890 | http://www.w3.org/2000/01/rdf-schema#comment | "Two alpha-type CK2-activated PKAs (CK2-aPKAIalpha and CK2-aPKAIIalpha) were biochemically characterized in vitro using GST-HBV core fusion protein (GST-Hcore) and GST-Hcore157B as phosphate acceptors. It was found that (i), in the absence of cAMP, these two CK2-aPKAs phosphorylated both Ser-170 and Ser-178 on GST-Hcore and Hcore157B; (ii) this phosphorylation was approx. 4-fold higher than their phosphorylation by cAMP-activated PKAs; and (iii) suramin effectively inhibited the phosphorylation of Hcore157B by CK2-aPKAIIalpha through its direct binding to Hcore157B in vitro. These results suggest that high phosphorylation of HBV-CP by two CK2-aPKAs, in the absence of cAMP, may be involved in the pregenomic RNA (pgRNA) encapsidation and DNA-replication in HBV-infected cells."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2006.01.011"xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/author | "Kuroki K."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/author | "Yamano Y."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/author | "Enomoto M."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/author | "Sawano Y."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/author | "Ohtsuki K."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/author | "Kosuge S."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/pages | "894-899"xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/title | "High phosphorylation of HBV core protein by two alpha-type CK2-activated cAMP-dependent protein kinases in vitro."xsd:string |
http://purl.uniprot.org/citations/16430890 | http://purl.uniprot.org/core/volume | "580"xsd:string |
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