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http://purl.uniprot.org/citations/16446092http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16446092http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16446092http://www.w3.org/2000/01/rdf-schema#comment"A series of novel benzoxazole benzenesulfonamides was synthesized as inhibitors of fructose-1,6-bisphosphatase (FBPase-1). Extensive SAR studies led to a potent inhibitor, 53, with an IC(50) of 0.57microM. Compound 17 exhibited excellent bioavailability and a good pharmacokinetic profile in rats."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2006.01.014"xsd:string
http://purl.uniprot.org/citations/16446092http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2006.01.014"xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Abad-Zapatero C."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Abad-Zapatero C."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Lai C."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Lai C."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Daly M."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Daly M."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Hutchins C."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Hutchins C."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Fry E.H."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Fry E.H."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"von Geldern T.W."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"von Geldern T.W."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Gum R.J."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/author"Gum R.J."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/name"Bioorg. Med. Chem. Lett."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/name"Bioorg. Med. Chem. Lett."xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/pages"1807-1810"xsd:string
http://purl.uniprot.org/citations/16446092http://purl.uniprot.org/core/pages"1807-1810"xsd:string