| http://purl.uniprot.org/citations/16446438 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16446438 | http://www.w3.org/2000/01/rdf-schema#comment | "Nod1, a cytosolic protein that senses meso-diaminopimelic acid-containing ligands derived from peptidoglycan, plays a role in host responses to invasive bacteria. Here we describe a function for Nod1, whereby it controls tumor formation. Cell lines derived from the human breast cancer epithelial cell line MCF-7 were used in a severe combined immune deficiency (SCID) mouse xenograft model to characterize a pathway linking Nod1 to the growth of estrogen-sensitive tumors. In MCF-7 cells, the absence of Nod1 correlates with tumor growth, an increased sensitivity to estrogen-induced cell proliferation, and a failure to undergo Nod1-dependent apoptosis. Conversely, overexpression of Nod1 in MCF-7 cells results in inhibition of estrogen-dependent tumor growth and reduction of estrogen-induced proliferative responses in vitro."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0509228103"xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Han J."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Li Q."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Zhou H."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Hsu J."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Mathison J."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Xiang R."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "da Silva Correia J."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Ulevitch R.J."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Austin-Brown N."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/author | "Miranda Y."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/pages | "1840-1845"xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/title | "Nod1-dependent control of tumor growth."xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://purl.uniprot.org/core/volume | "103"xsd:string |
| http://purl.uniprot.org/citations/16446438 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16446438 |
| http://purl.uniprot.org/citations/16446438 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16446438 |
| http://purl.uniprot.org/uniprot/#_A0A024RA73-mappedCitation-16446438 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16446438 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z4W5-mappedCitation-16446438 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16446438 |
| http://purl.uniprot.org/uniprot/#_B3KN80-mappedCitation-16446438 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16446438 |
| http://purl.uniprot.org/uniprot/#_G3XAL1-mappedCitation-16446438 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16446438 |
| http://purl.uniprot.org/uniprot/#_Q7Z2K1-mappedCitation-16446438 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16446438 |