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http://purl.uniprot.org/citations/16451087http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16451087http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16451087http://www.w3.org/2000/01/rdf-schema#comment"A series of novel indole-based PPAR agonists is described leading to discovery of 10k, a highly potent PPAR pan-agonist. The structural biology and molecular docking studies revealed that the distances between the acidic group and the linker, when a ligand was complexed with PPARgamma protein, were important for the potent activity. The hydrophobic tail part of 10k makes intensive hydrophobic interaction with the PPARgamma protein resulting in potent activity."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.org/dc/terms/identifier"doi:10.1021/jm0510373"xsd:string
http://purl.uniprot.org/citations/16451087http://purl.org/dc/terms/identifier"doi:10.1021/jm0510373"xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Chen X."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Chen X."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Peng Y.-H."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Peng Y.-H."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Lin Y.-T."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Lin Y.-T."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Tsai C.-H."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Tsai C.-H."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Huang W.-J."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Huang W.-J."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Liao C.-C."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Liao C.-C."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Lin C.-H."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Lin C.-H."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Wang C.-C."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Wang C.-C."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Huang C.-F."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Huang C.-F."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Wu S.-Y."xsd:string
http://purl.uniprot.org/citations/16451087http://purl.uniprot.org/core/author"Wu S.-Y."xsd:string