| http://purl.uniprot.org/citations/16455976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16455976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16455976 | http://www.w3.org/2000/01/rdf-schema#comment | "Based on phylogenetic analysis and chromosomal mapping, the orphan receptor RDC1 was proposed to be a chemokine receptor. In this study we examined the expression of RDC1 on leukocytes by measuring mRNA levels and receptor expression using a new specific mAb. Both mRNA and protein levels were high in monocytes and B cells, relatively low on immature dendritic cells (DC), and up-regulated during final stages of maturation. Strikingly, in mature plasmacytoid DC the mRNA was up-regulated, but did not correlate with protein surface expression. We indeed report that CpG-activated plasmacytoid DC produce a putative ligand for RDC1, which selectively down-regulates RDC1, but not CXCR4 on primary human B cells. RDC1 expression was found to be tightly regulated during B cell development and differentiation. In blood-derived switch memory B cells, the expression of RDC1 appeared to correlate with the ability to differentiate into plasma cells upon activation, suggesting that RDC1 is a marker for memory B cells, which are competent to become Ab-secreting cells."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.176.4.2197"xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.176.4.2197"xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/author | "Thelen M."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/author | "Thelen M."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/author | "Infantino S."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/author | "Infantino S."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/author | "Moepps B."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/author | "Moepps B."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/pages | "2197-2207"xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/pages | "2197-2207"xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/title | "Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/title | "Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells."xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/volume | "176"xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://purl.uniprot.org/core/volume | "176"xsd:string |
| http://purl.uniprot.org/citations/16455976 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16455976 |
| http://purl.uniprot.org/citations/16455976 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16455976 |
| http://purl.uniprot.org/citations/16455976 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16455976 |
| http://purl.uniprot.org/citations/16455976 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16455976 |