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http://purl.uniprot.org/citations/16457793http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16457793http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16457793http://www.w3.org/2000/01/rdf-schema#comment"Alpha (alpha) catenin proteins can regulate both cell adhesion and cell proliferation. Here, we characterize the expression of two forms of alpha-catenin, alphaE-catenin and alphaN-catenin, in the developing cerebral cortex and primary cortical cultures. In situ hybridization and immunofluorescence studies reveal that alphaE-catenin is highly expressed in neuroepithelial precursor cells in the developing cortical ventricular zone, with markedly reduced expression in the cortical plate; in contrast, alphaN-catenin expression is low in the ventricular zone and high in the developing cortical plate. In the ventricular zone, immunoreactivity for both alphaE-catenin and alphaN-catenin is enriched in rings at the lumenal surface, reflecting localization at adherens junctions together with beta-catenin. Expression of alphaE-catenin in primary cortical precursor cultures is initially robust, but declines as neural precursors differentiate into neurons. Reflecting its expression pattern in vivo, alphaN-catenin is expressed in both neural precursors as well in neurons differentiated in culture. These differential expression patterns of alphaE-catenin and alphaN-catenin suggest both distinct and overlapping functions during cortical development."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.org/dc/terms/identifier"doi:10.1016/j.brainres.2005.12.057"xsd:string
http://purl.uniprot.org/citations/16457793http://purl.org/dc/terms/identifier"doi:10.1016/j.brainres.2005.12.057"xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/author"Chenn A."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/author"Chenn A."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/author"Stocker A.M."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/author"Stocker A.M."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/name"Brain Res."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/name"Brain Res."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/pages"151-158"xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/pages"151-158"xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/title"Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/title"Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex."xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/volume"1073"xsd:string
http://purl.uniprot.org/citations/16457793http://purl.uniprot.org/core/volume"1073"xsd:string
http://purl.uniprot.org/citations/16457793http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16457793
http://purl.uniprot.org/citations/16457793http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16457793
http://purl.uniprot.org/citations/16457793http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16457793
http://purl.uniprot.org/citations/16457793http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16457793
http://purl.uniprot.org/uniprot/Q61301http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/16457793
http://purl.uniprot.org/uniprot/Q61301#attribution-11CCBFC6B6D3EA23C7CF116F6CA80121http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16457793