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http://purl.uniprot.org/citations/16461884http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16461884http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16461884http://www.w3.org/2000/01/rdf-schema#comment"Pericentromeres are exceptional genomic regions: in animals they contain extensive segmental duplications implicated in gene creation, and in plants they sustain rearrangements and insertions uncommon in euchromatin. To examine the mechanisms and patterns of plant pericentromere evolution, we compared pericentromere sequence from four Brassicaceae species separated by <15 million years (Myr). This flowering plant family is ideal for studying relationships between genome reorganization and pericentromere evolution-its members have undergone recent polyploidization and hybridization, with close relatives changing in genome size and chromosome number. Through sequence and hybridization analyses, we examined regions from Arabidopsis arenosa, Capsella rubella, and Olimarabidopsis pumila that are homologous to Arabidopsis thaliana pericentromeres (peri-CENs) III and V, and used FISH to demonstrate they have been maintained near centromere satellite arrays in each species. Sequence analysis revealed a set of highly conserved genes, yet we discovered substantial differences in intergenic length and species-specific changes in sequence content and gene density. We discovered that A. thaliana has undergone recent, significant expansions within its pericentromeres, in some cases measuring hundreds of kilobases; these findings are in marked contrast to euchromatic segments in these species that exhibit only minor length changes. While plant pericentromeres do contain some duplications, we did not find evidence of extensive segmental duplications, as has been documented in primates. Our data support a model in which plant pericentromeres may experience selective pressures distinct from euchromatin, tolerating rapid, dynamic changes in structure and sequence content, including large insertions of mobile elements, 5S rDNA arrays and pseudogenes."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.org/dc/terms/identifier"doi:10.1101/gr.4399206"xsd:string
http://purl.uniprot.org/citations/16461884http://purl.org/dc/terms/identifier"doi:10.1101/gr.4399206"xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/author"Kettler G.C."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/author"Kettler G.C."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/author"Preuss D."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/author"Preuss D."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/author"Hall A.E."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/author"Hall A.E."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/name"Genome Res."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/name"Genome Res"xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/pages"355-364"xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/pages"355-364"xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/title"Dynamic evolution at pericentromeres."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/title"Dynamic evolution at pericentromeres."xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/volume"16"xsd:string
http://purl.uniprot.org/citations/16461884http://purl.uniprot.org/core/volume"16"xsd:string
http://purl.uniprot.org/citations/16461884http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16461884
http://purl.uniprot.org/citations/16461884http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16461884
http://purl.uniprot.org/citations/16461884http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16461884
http://purl.uniprot.org/citations/16461884http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16461884