| http://purl.uniprot.org/citations/16472766 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16472766 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16472766 | http://www.w3.org/2000/01/rdf-schema#comment | "The autoantigen Ro52 is an E3 ubiquitin ligase that can ubiquitinate itself (self-ubiquitination). Recently, we showed that UnpEL/Usp4 is an isopeptidase that can deconjugate ubiquitin from self-ubiquitinated Ro52. Here, we showed that UnpEL is ubiquitinated by Ro52 in cooperation with UbcH5B in vitro. We also showed that UnpEL is ubiquitinated by Ro52 in HEK293T cells. Interestingly, a catalytically inactive UnpEL mutant was strongly ubiquitinated by Ro52 in HEK293T cells. These results suggest that wild-type UnpEL is ubiquitinated by Ro52 and deubiquitinated by itself (self-deubiquitination), while mutant UnpEL is ubiquitinated by Ro52 but not deubiquitinated by itself. In conclusion, Ro52 and UnpEL transregulate each other by ubiquitination and deubiquitination."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2006.01.144"xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2006.01.144"xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/author | "Wada K."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/author | "Wada K."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/author | "Kamitani T."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/author | "Kamitani T."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/pages | "253-258"xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/pages | "253-258"xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/title | "UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/title | "UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself."xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/volume | "342"xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://purl.uniprot.org/core/volume | "342"xsd:string |
| http://purl.uniprot.org/citations/16472766 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16472766 |
| http://purl.uniprot.org/citations/16472766 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16472766 |
| http://purl.uniprot.org/citations/16472766 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16472766 |
| http://purl.uniprot.org/citations/16472766 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16472766 |
| http://purl.uniprot.org/uniprot/Q13107 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16472766 |
| http://purl.uniprot.org/uniprot/P19474 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16472766 |