http://purl.uniprot.org/citations/16481471 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16481471 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16481471 | http://www.w3.org/2000/01/rdf-schema#comment | "Genetic redundancy is associated with a large percentage of genes. We investigated PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor gene functions that eluded single mutant analyses, using a Caenorhabditis elegans genome-wide screen. We show that at least 27 genes collaborate with the worm PTEN homolog daf-18 for various functions previously concealed by genetic redundancy, including embryogenesis, cuticle turnover, egg laying, and oocyte maturation. In one example, daf-18 appears to constitute a cell-autonomous germline signal that converges with a somatic gonad signal mediated by ceh-18 at a kinase inhibition. We provide evidence that daf-18 elicits some functions independent of the downstream gene daf-16."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.1378906"xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.1378906"xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/author | "Han M."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/author | "Han M."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/author | "Suzuki Y."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/author | "Suzuki Y."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/pages | "423-428"xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/pages | "423-428"xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/title | "Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/title | "Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development."xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/volume | "20"xsd:string |
http://purl.uniprot.org/citations/16481471 | http://purl.uniprot.org/core/volume | "20"xsd:string |
http://purl.uniprot.org/citations/16481471 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16481471 |
http://purl.uniprot.org/citations/16481471 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16481471 |
http://purl.uniprot.org/citations/16481471 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16481471 |
http://purl.uniprot.org/citations/16481471 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16481471 |
http://purl.uniprot.org/uniprot/G5EE01 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16481471 |
http://purl.uniprot.org/uniprot/G5EE01#attribution-7774E5B91B30A5AFC66FAC6BE01B57C4 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16481471 |