http://purl.uniprot.org/citations/16489264 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16489264 | http://www.w3.org/2000/01/rdf-schema#comment | "HLA alleles have been associated with psoriasis. Toxin-producing strains of Staphylococcus aureus behave as superantigens, and if present in patients, might play a role in the exacerbation of psoriatic lesions by activating certain V-beta (V beta) T-lymphocyte subsets. Allele frequencies in 22 patients and 22 controls (alleles determined by DNA/SSP typing) were used to calculate a relative risk of $4.7$ ($P < .05$) for HLA-Cw6. S aureus was isolated from the throat of 11 patients. Enterotoxins A and C were detected by agglutination in the culture filtrate of one isolate. The enterotoxin A and/or C genes were detected by PCR in 9 isolates, and transcripts were detected by RT-PCR in 7 of them. None of the isolates from controls harbored enterotoxin genes. V beta expansions were detected by RT-PCR in all 22 patients. Low or no V beta expansions were obtained in controls. The association of HLA-Cw6 with psoriasis in Lebanese concurs with that reported for other ethnic groups. Toxin-producing isolates that colonize patients might play a role in the exacerbation of psoriatic lesions."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.org/dc/terms/identifier | "doi:10.1155/jbb.2005.310"xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/author | "Kibbi A.G."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/author | "Matar G.M."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/author | "Abdelnoor A.M."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/author | "Rahal E."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/author | "Ajib R."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/author | "Janbazian L."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/author | "Zaynoun S."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/name | "J Biomed Biotechnol"xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/pages | "310-315"xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/title | "HLA allele associations and V-beta T-lymphocyte expansions in patients with psoriasis, harboring toxin-producing Staphylococcus aureus."xsd:string |
http://purl.uniprot.org/citations/16489264 | http://purl.uniprot.org/core/volume | "2005"xsd:string |
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