| http://purl.uniprot.org/citations/16496041 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16496041 | http://www.w3.org/2000/01/rdf-schema#comment | "hnRNP K protein, which localizes to the nucleus, cytoplasm and mitochondria, is involved in the various cellular processes that compose gene expression. We used a SAGE-based assay to profile RNAs associated with hnRNP K protein in rat mitochondria. RNA was isolated from mitoplasts obtained from highly purified and RNase-treated mitochondria. Total RNA and RNA associated with hnRNP K protein were then used as input material for generating two SAGE libraries. Mitochondrion-derived tags isolated from the total mitoplast RNA library represented 86.3%, while those isolated from the library constructed from RNA associated with hnRNP K protein represented only 28.2% of selected tags. Thus, an unexpected number of nuclear-encoded RNAs were purified from mitochondria. Many of these transcripts were co-purified with hnRNP K protein, and high levels of nuclear-encoded RNAs co-immunoprecipitating with K protein corresponded to elevated hnRNP K protein levels of the organelle. The most abundant RNAs that were co-purified with hnRNP K protein represented transcripts originating from satellite I DNA. While satellite I RNA levels were higher in the nucleus and cytoplasm than in mitochondria, the most abundant binding of satellite I transcripts to hnRNP K protein was found in mitochondria. The role of satellite I RNA in mitochondria remains to be elucidated."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/author | "Wyrwicz L.S."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/author | "Ostrowski J."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/author | "Paziewska A."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/author | "Hennig E.E."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/author | "Mikula M."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/author | "Dzwonek A."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/author | "Klimek-Tomczak K."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/name | "Acta Biochim Pol"xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/pages | "169-178"xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/title | "Mitochondria-associated satellite I RNA binds to hnRNP K protein."xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://purl.uniprot.org/core/volume | "53"xsd:string |
| http://purl.uniprot.org/citations/16496041 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16496041 |
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