| http://purl.uniprot.org/citations/16499869 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16499869 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16499869 | http://www.w3.org/2000/01/rdf-schema#comment | "Human gene RFP2 is a candidate tumor suppressor located at 13q14.3 and deleted in multiple tumor types. To explore regulation of RFP2, we determined structure of the 5'-untranslated region of RFP2 gene and its promoter. RFP2 promoter area is TATA-less, highly enriched in G and C nucleotides, and contains multiple quadruplex forming GGGGA-repeats. Deletion analysis of 5'-flanking sequences demonstrated that repeat containing fragment possesses activity seven times exceeding that of the combined SV40 promoter/enhancer. Other unusual features of the RFP2 promoter include anomalously high electrostatic fields induced by sequence-dependent dipoles and very low nucleosome forming potential. A "minimized" version of the RFP2 promoter could be used for overexpression of the various transgenes in the mammalian cells."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2006.01.187"xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2006.01.187"xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Ivanov D."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Ivanov D."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Skoblov M."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Skoblov M."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Rubtsov P."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Rubtsov P."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Baranova A."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Baranova A."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Yankovsky N."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Yankovsky N."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Guskova A."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Guskova A."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Ivanov D.'"xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Ivanov D.'"xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Oshchepkov D."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Oshchepkov D."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Prasolov V."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Prasolov V."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Shakhbazov K."xsd:string |
| http://purl.uniprot.org/citations/16499869 | http://purl.uniprot.org/core/author | "Shakhbazov K."xsd:string |