| http://purl.uniprot.org/citations/16509598 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16509598 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16509598 | http://www.w3.org/2000/01/rdf-schema#comment | "Two series of P1'-extended HIV-1 protease inhibitors comprising a tertiary alcohol in the transition-state mimic exhibiting Ki values ranging from 2.1 to 93 nM have been synthesized. Microwave-accelerated palladium-catalyzed cross-couplings were utilized to rapidly optimize the P1' side chain. High cellular antiviral potencies were encountered when the P1' benzyl group was elongated with a 3- or 4-pyridyl substituent (EC50 = 0.18-0.22 microM). X-ray crystallographic data were obtained for three inhibitors cocrystallized with the enzyme."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.org/dc/terms/identifier | "doi:10.1021/jm051239z"xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.org/dc/terms/identifier | "doi:10.1021/jm051239z"xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Johansson A."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Johansson A."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Unge T."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Unge T."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Samuelsson B."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Samuelsson B."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Hallberg A."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Hallberg A."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Larhed M."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Larhed M."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Ekegren J.K."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Ekegren J.K."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Ginman N."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Ginman N."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Wallberg H."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/author | "Wallberg H."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/name | "J. Med. Chem."xsd:string |
| http://purl.uniprot.org/citations/16509598 | http://purl.uniprot.org/core/name | "J Med Chem"xsd:string |