http://purl.uniprot.org/citations/16522456 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16522456 | http://www.w3.org/2000/01/rdf-schema#comment | "The contribution of CD8+ T cells to the development of airway hyperresponsiveness and airway inflammation has received increased attention recently. CD8+ T cells, which are capable of secreting TH2 cytokines, including IL-4, IL-5, and IL-13, have been described in asthmatic subjects and in animals sensitized and challenged with allergen. A subset of these IL-13-producing CD8+ T cells, effector memory CD8+ T cells in the mouse, express a high-affinity receptor for leukotriene B4 (BLT1), and expression of this receptor is essential for their accumulation in the lung and development of airway hyperresponsiveness and airway inflammation. A similar subset of CD8+/BLT1+/IL-13+ T cells has also been identified in the bronchoalveolar lavage fluid of asthmatic subjects, suggesting a pathogenic role for this unique subset of CD8+ T cells in asthma."xsd:string |
http://purl.uniprot.org/citations/16522456 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jaci.2005.12.1340"xsd:string |
http://purl.uniprot.org/citations/16522456 | http://purl.uniprot.org/core/author | "Gelfand E.W."xsd:string |
http://purl.uniprot.org/citations/16522456 | http://purl.uniprot.org/core/author | "Dakhama A."xsd:string |
http://purl.uniprot.org/citations/16522456 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16522456 | http://purl.uniprot.org/core/name | "J Allergy Clin Immunol"xsd:string |
http://purl.uniprot.org/citations/16522456 | http://purl.uniprot.org/core/pages | "577-582"xsd:string |
http://purl.uniprot.org/citations/16522456 | http://purl.uniprot.org/core/title | "CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma."xsd:string |
http://purl.uniprot.org/citations/16522456 | http://purl.uniprot.org/core/volume | "117"xsd:string |
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