| http://purl.uniprot.org/citations/16532012 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16532012 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16532012 | http://www.w3.org/2000/01/rdf-schema#comment | "Biosynthesis of heparin, a mast cell-derived glycosaminoglycan with widespread importance in medicine, has not been fully elucidated. In biosynthesis of heparan sulfate (HS), a structurally related polysaccharide, HS glucuronyl C5-epimerase (Hsepi) converts D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) residues. We have generated Hsepi-null mouse mutant mast cells, and we show that the same enzyme catalyzes the generation of IdoA in heparin and that 'heparin' lacking IdoA shows a distorted O-sulfation pattern."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.org/dc/terms/identifier | "doi:10.1038/nchembio777"xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.org/dc/terms/identifier | "doi:10.1038/nchembio777"xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Li J.P."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Li J.P."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Rodewald H.R."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Rodewald H.R."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Lindahl U."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Lindahl U."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Feyerabend T.B."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/author | "Feyerabend T.B."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/name | "Nat. Chem. Biol."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/name | "Nat. Chem. Biol."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/pages | "195-196"xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/pages | "195-196"xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/title | "Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/title | "Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells."xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/16532012 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16532012 |
| http://purl.uniprot.org/citations/16532012 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16532012 |