http://purl.uniprot.org/citations/16533342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16533342 | http://www.w3.org/2000/01/rdf-schema#comment | "ProblemThe objective of this study was to identify the human leukocyte antigen (HLA) alleles that confer susceptibility or resistance to polycystic ovary syndrome (PCOS) in the Japanese population.Method of studyHLA-A, -B and -C antigens were determined in 56 patients with PCOS using conventional serological method. HLA-DRB1 genotypes were determined using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 68 patients with PCOS. As a control population, 237 healthy individuals (males and females) were examined concerning HLA-A, -B and -C antigens, and 292 individuals were examined concerning HLA-DRB1 genotypes. The rate of possession of each antigen was compared between the two populations.ResultsThe rate of possession of the HLA-A11 and HLA-DRB1*0403 in the patients with PCOS was significantly higher compared with that in the control group. The rate of possession of HLA-B39 in the patients with PCOS was significantly lower compared with that in the general population group.ConclusionHuman leukocyte antigen systems appear to be linked to PCOS."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1600-0897.2006.00369.x"xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/author | "Tanaka K."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/author | "Ishii K."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/author | "Tamura M."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/author | "Takakuwa K."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/author | "Kaibe M."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/author | "Murakawa H."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/name | "Am J Reprod Immunol"xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/pages | "301-306"xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/title | "Studies on the human leukocyte antigens in patients with polycystic ovary syndrome in a Japanese population--possible susceptibility of HLA-A11 and -DRB1*0403 to patient population with polycystic ovary syndrome."xsd:string |
http://purl.uniprot.org/citations/16533342 | http://purl.uniprot.org/core/volume | "55"xsd:string |
http://purl.uniprot.org/citations/16533342 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16533342 |
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