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| http://purl.uniprot.org/citations/16543460 | http://www.w3.org/2000/01/rdf-schema#comment | "During development, cells monitor and adjust their rates of accumulation to produce organs of predetermined size. We show here that central nervous system-specific deletion of the essential adherens junction gene, alphaE-catenin, causes abnormal activation of the hedgehog pathway, resulting in shortening of the cell cycle, decreased apoptosis, and cortical hyperplasia. We propose that alphaE-catenin connects cell-density-dependent adherens junctions with the developmental hedgehog pathway and that this connection may provide a negative feedback loop controlling the size of developing cerebral cortex."xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1121449"xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/author | "Delrow J."xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/author | "Vasioukhin V."xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/author | "Klezovitch O."xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/author | "Fernandez T.E."xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/author | "Lien W.H."xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/pages | "1609-1612"xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/title | "alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway."xsd:string |
| http://purl.uniprot.org/citations/16543460 | http://purl.uniprot.org/core/volume | "311"xsd:string |
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