| http://purl.uniprot.org/citations/16546177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16546177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16546177 | http://www.w3.org/2000/01/rdf-schema#comment | "Stimulation of Dictyostelium cells with the chemoattractant cAMP results in transient phosphorylation of the myosin regulatory light chain (RLC). We show that myosin light chain kinase A (MLCK-A) is responsible for RLC phosphorylation during chemotaxis, and that MLCK-A itself is transiently phosphorylated on threonine-166, dramatically increasing its catalytic activity. MLCK-A activation during chemotaxis is highly responsive to cellular cGMP levels and the cGMP-binding protein GbpC. MLCK-A-cells have a partial cytokinesis defect, and do not phosphorylate RLC in response to concanavalin A (conA), but cells lacking cGMP or GbpC divide normally and phosphorylate in response to conA. Thus MLCK-A is activated by a cGMP/GbpC-independent mechanism activated during cytokinesis or by conA, and a cGMP/GbpC-dependent pathway during chemotaxis."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2006.03.008"xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2006.03.008"xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Goldberg J.M."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Goldberg J.M."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Smith J.L."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Smith J.L."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Van Haastert P.J.M."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Van Haastert P.J.M."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Bosgraaf L."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Bosgraaf L."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Clarkson B.K."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Clarkson B.K."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Wolpin E.S."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/author | "Wolpin E.S."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/pages | "2059-2064"xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/pages | "2059-2064"xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/title | "Myosin light chain kinase A is activated by cGMP-dependent and cGMP-independent pathways."xsd:string |
| http://purl.uniprot.org/citations/16546177 | http://purl.uniprot.org/core/title | "Myosin light chain kinase A is activated by cGMP-dependent and cGMP-independent pathways."xsd:string |