http://purl.uniprot.org/citations/16564389 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16564389 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectivesTo evaluate the impact of clinical, histopathological, and molecular biological parameters on the prognosis of nasopharyngeal carcinoma (NPC).Study design and settingThe clinical records of 48 patients with a diagnosis of NPC were retrospectively reviewed. In situ hybridization for Epstein-Barr virus encoded small RNA 1 (EBER-ISH) was applied for 30 paraffin-embedded specimens available. Prognostic factors of NPC were meticulously analyzed.ResultsThe EBER-ISH signal was shown to be highly significant as a favorable prognostic factor (P = 0.007). Although EBV was more commonly associated with Type III NPC, EBER-ISH-positive Type I-II NPC had also significantly better survival rate than EBER-ISH-negative Type I-II NPC (P = 0.036).ConclusionsIn addition to the WHO histopathological grade, the 1997 UICC staging, nodal status, and distant metastasis at presentation, the EBER-ISH signal was shown to be significant as a prognostic factor.SignificanceThis is the first report to describe the EBER-ISH as an independent prognostic factor of NPC regardless of histopathology.Ebm ratingB-2b."xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.otohns.2005.11.022"xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/author | "Nakao K."xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/author | "Sugasawa M."xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/author | "Nibu K."xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/author | "Uozaki H."xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/author | "Mochiki M."xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/name | "Otolaryngol Head Neck Surg"xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/pages | "639-645"xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/title | "Analysis of prognostic factors of nasopharyngeal carcinoma: impact of in situ hybridization for Epstein-Barr virus encoded small RNA 1."xsd:string |
http://purl.uniprot.org/citations/16564389 | http://purl.uniprot.org/core/volume | "134"xsd:string |
http://purl.uniprot.org/citations/16564389 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16564389 |
http://purl.uniprot.org/citations/16564389 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16564389 |
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http://purl.uniprot.org/uniprot/Q9BYF5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16564389 |