http://purl.uniprot.org/citations/16567368 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16567368 | http://www.w3.org/2000/01/rdf-schema#comment | "The crystal structure of the seed lectin from the tropical legume Bowringia milbraedii was determined in complex with the disaccharide ligand Man(alpha1-2)Man. In solution, the protein exhibits a dynamic dimer-tetramer equilibrium, consistent with the concanavalin A-type tetramer observed in the crystal. Contacts between the tetramers are mediated almost exclusively through the carbohydrate ligand, resulting in a crystal lattice virtually identical to that of the concanavalin-A:Man(alpha1-2)Man complex, even though both proteins have less than 50% sequence identity. The disaccharide binds exclusively in a "downstream" binding mode, with the non-reducing mannose occupying the monosaccharide-binding site. The reducing mannose is bound in a predominantly polar subsite involving Tyr131, Gln218, and Tyr219."xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.org/dc/terms/identifier | "doi:10.1093/glycob/cwj109"xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/author | "Wyns L."xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/author | "Garcia-Pino A."xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/author | "Loris R."xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/author | "Buts L."xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/name | "Glycobiology"xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/pages | "635-640"xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/title | "Structural basis of carbohydrate recognition by a Man(alpha1-2)Man-specific lectin from Bowringia milbraedii."xsd:string |
http://purl.uniprot.org/citations/16567368 | http://purl.uniprot.org/core/volume | "16"xsd:string |
http://purl.uniprot.org/citations/16567368 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16567368 |
http://purl.uniprot.org/citations/16567368 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16567368 |
http://purl.uniprot.org/uniprot/#_P42088-mappedCitation-16567368 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16567368 |
http://purl.uniprot.org/uniprot/P42088 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16567368 |