| http://purl.uniprot.org/citations/16571411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16571411 | http://www.w3.org/2000/01/rdf-schema#comment | "Natural killer (NK) cells are key components of the innate antiviral immune response. NK cell function is regulated by the interaction of major histocompatibility complex class I molecules with NK inhibitory receptors. The aim of this study was to investigate the role of the HLA-C/KIR pair in hepatitis C virus clearance in our population. A total of 196 hepatitis C virus-infected patients (65 resolved and 131 with persistent infection) were included in the study. Genotyping of HLA-C was carried out using polymerase chain reaction followed by a reverse sequence-specific oligonucleotide probe detection system. NK receptor-specific polymerase chain reaction typing of KIR2DL1, KIR2DL2, and KIR2DL3 was performed on the same patient group. Frequencies of the KIR2DL2 gene and the KIR2DL2/KIR2DL2 genotype were lower among patients with persistent infection (32.3% vs 45.4% among resolved, P = 0.01, OR = 0.57, 95% CI = 0.36-0.91; and 16.2% vs 32.3% among resolved, P = 0.02, OR = 0.41, 95% CI = 0.19-0.87). Nevertheless, the frequency of the KIR2DL3 gene was higher among patients with persistent infection (66.9% vs 54.6% among resolved P = 0.02, OR = 1.68, 95% CI = 1.07-2.65). Trends toward lower frequencies of the HLA-C2C2 genotype and NK-HLA interactions with strong and moderate affinity among the patients with persistent infection were also observed."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.humimm.2006.02.001"xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Andrade R."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Gonzalez-Escribano M.F."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Nunez-Roldan A."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Montes-Cano M.A."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Romero-Gomez M."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Aguilar Reina J."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Carmona I."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Caro-Oleas J.L."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/author | "Diago M."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/name | "Hum Immunol"xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/pages | "1106-1109"xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/title | "HLA-C and KIR genes in hepatitis C virus infection."xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://purl.uniprot.org/core/volume | "66"xsd:string |
| http://purl.uniprot.org/citations/16571411 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16571411 |
| http://purl.uniprot.org/citations/16571411 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16571411 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-16571411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16571411 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C553-mappedCitation-16571411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16571411 |
| http://purl.uniprot.org/uniprot/#_A0A089N0V0-mappedCitation-16571411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16571411 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C850-mappedCitation-16571411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16571411 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C8P1-mappedCitation-16571411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16571411 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C8P4-mappedCitation-16571411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16571411 |