| http://purl.uniprot.org/citations/16572171 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16572171 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16572171 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16572171 | http://www.w3.org/2000/01/rdf-schema#comment | "Here we present a finished sequence of human chromosome 15, together with a high-quality gene catalogue. As chromosome 15 is one of seven human chromosomes with a high rate of segmental duplication, we have carried out a detailed analysis of the duplication structure of the chromosome. Segmental duplications in chromosome 15 are largely clustered in two regions, on proximal and distal 15q; the proximal region is notable because recombination among the segmental duplications can result in deletions causing Prader-Willi and Angelman syndromes. Sequence analysis shows that the proximal and distal regions of 15q share extensive ancient similarity. Using a simple approach, we have been able to reconstruct many of the events by which the current duplication structure arose. We find that most of the intrachromosomal duplications seem to share a common ancestry. Finally, we demonstrate that some remaining gaps in the genome sequence are probably due to structural polymorphisms between haplotypes; this may explain a significant fraction of the gaps remaining in the human genome."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature04601"xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature04601"xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature04601"xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Abouelleil A."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Abouelleil A."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Abouelleil A."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Arachchi H.M."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Arachchi H.M."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Arachchi H.M."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Abbasi N."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Abbasi N."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Abbasi N."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Birren B.W."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Birren B.W."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Birren B.W."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Bloom T."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Bloom T."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Bloom T."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Borowsky M.L."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Borowsky M.L."xsd:string |
| http://purl.uniprot.org/citations/16572171 | http://purl.uniprot.org/core/author | "Borowsky M.L."xsd:string |