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http://purl.uniprot.org/citations/16573737http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16573737http://www.w3.org/2000/01/rdf-schema#comment"Cells of Dictyostelium discoideum become sexually mature when submerged and in darkness, and fuse with opposite mating-type cells as gametes. The gene for a Rho GTPase, RacF2, is one of the extremely gamete-enriched genes (>100-fold) identified by us previously. Here, we isolated knockout, overexpression, constitutively active and dominant negative mutants of RacF2, and analyzed their phenotypes. These mutants showed anomalies in the extent of sexual cell fusion and asexual development as well as in EDTA-sensitive cell-cell adhesion. It is suggested that RacF2 controls the process of sexual and asexual development through the regulation of cellular adhesiveness. An analysis of the expression of all 18 rac family genes by real-time polymerase chain reaction revealed that four additional genes, rac1b, rac1c, racF1 and racG, were induced during maturation, suggesting their possible involvement in sexual cell interactions."xsd:string
http://purl.uniprot.org/citations/16573737http://purl.org/dc/terms/identifier"doi:10.1111/j.1440-169x.2006.00857.x"xsd:string
http://purl.uniprot.org/citations/16573737http://purl.uniprot.org/core/author"Urushihara H."xsd:string
http://purl.uniprot.org/citations/16573737http://purl.uniprot.org/core/author"Muramoto T."xsd:string
http://purl.uniprot.org/citations/16573737http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16573737http://purl.uniprot.org/core/name"Dev Growth Differ"xsd:string
http://purl.uniprot.org/citations/16573737http://purl.uniprot.org/core/pages"199-208"xsd:string
http://purl.uniprot.org/citations/16573737http://purl.uniprot.org/core/title"Small GTPase RacF2 affects sexual cell fusion and asexual development in Dictyostelium discoideum through the regulation of cell adhesion."xsd:string
http://purl.uniprot.org/citations/16573737http://purl.uniprot.org/core/volume"48"xsd:string
http://purl.uniprot.org/citations/16573737http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16573737
http://purl.uniprot.org/citations/16573737http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16573737
http://purl.uniprot.org/uniprot/Q9GPQ8#attribution-84C6E0B662A65D934F9E06B64A180086http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/Q9GPS0#attribution-84C6E0B662A65D934F9E06B64A180086http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/P34146#attribution-84C6E0B662A65D934F9E06B64A180086http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/Q23862#attribution-84C6E0B662A65D934F9E06B64A180086http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/P34145#attribution-84C6E0B662A65D934F9E06B64A180086http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/O96390#attribution-84C6E0B662A65D934F9E06B64A180086http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/Q9GPS3#attribution-019AD89601322EECC0F6ED67C04FC896http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/Q9GPQ9#attribution-84C6E0B662A65D934F9E06B64A180086http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/#_O96390-mappedCitation-16573737http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/#_P34144-mappedCitation-16573737http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/#_P34145-mappedCitation-16573737http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/#_P34146-mappedCitation-16573737http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16573737
http://purl.uniprot.org/uniprot/#_P34147-mappedCitation-16573737http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16573737