| http://purl.uniprot.org/citations/16579989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16579989 | http://www.w3.org/2000/01/rdf-schema#comment | "Erythroid Krüppel-like factor (EKLF/KLF1) is an erythroid specific, C(2)H(2) zinc finger transcription factor that is essential for the proper chromatin structure and expression of the adult beta-globin gene. Herein, we determine that 26S proteasome inhibitors lead to an accumulation of EKLF protein in murine erythroleukemia (MEL) cells. In addition, EKLF half-life in both MEL cells (<3h) and fetal liver cells (between 6 and 9h) is stabilized in the presence of these inhibitors. EKLF is ubiquitinated in vivo, however its modification does not rely on a particular internal lysine. Finally, EKLF contains two PEST sequences within its N-terminus that have no effect on the ability of EKLF to be ubiquitinated but contribute to its destabilization."xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2006.03.039"xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://purl.uniprot.org/core/author | "Bieker J.J."xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://purl.uniprot.org/core/author | "Quadrini K.J."xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16579989 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://purl.uniprot.org/core/pages | "2285-2293"xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://purl.uniprot.org/core/title | "EKLF/KLF1 is ubiquitinated in vivo and its stability is regulated by activation domain sequences through the 26S proteasome."xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://purl.uniprot.org/core/volume | "580"xsd:string |
| http://purl.uniprot.org/citations/16579989 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16579989 |
| http://purl.uniprot.org/citations/16579989 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16579989 |
| http://purl.uniprot.org/uniprot/#_P0CG48-mappedCitation-16579989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16579989 |
| http://purl.uniprot.org/uniprot/#_Q13351-mappedCitation-16579989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16579989 |
| http://purl.uniprot.org/uniprot/P0CG48 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16579989 |
| http://purl.uniprot.org/uniprot/Q13351 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16579989 |