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http://purl.uniprot.org/citations/16580634http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16580634http://www.w3.org/2000/01/rdf-schema#comment"The LKB1/STK11 serine/threonine kinase is mutated in Peutz-Jeghers syndrome and various sporadic cancers such as lung adenocarcinoma. We show here that LKB1 forms a complex with LMO4, GATA-6, and Ldb1, and enhances GATA-mediated transactivation in a kinase-dependent manner. We further demonstrate that LKB1 has the potential to induce p21 expression in collaboration with LMO4, GATA-6, and Ldb1 through the p53-independent mechanism. Our findings suggest that LKB1 regulates GATA-mediated gene expression and that this activity of LKB1 may be important for its tumor suppressor function."xsd:string
http://purl.uniprot.org/citations/16580634http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2006.03.077"xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/author"Masuda T."xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/author"Matsuura K."xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/author"Akiyama T."xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/author"Shinozaki-Yabana S."xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/author"Setogawa T."xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/pages"1186-1190"xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/title"The tumor suppressor LKB1 induces p21 expression in collaboration with LMO4, GATA-6, and Ldb1."xsd:string
http://purl.uniprot.org/citations/16580634http://purl.uniprot.org/core/volume"343"xsd:string
http://purl.uniprot.org/citations/16580634http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16580634
http://purl.uniprot.org/citations/16580634http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16580634
http://purl.uniprot.org/uniprot/#_D4P556-mappedCitation-16580634http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16580634
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http://purl.uniprot.org/uniprot/#_Q15831-mappedCitation-16580634http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16580634
http://purl.uniprot.org/uniprot/#_Q59ED0-mappedCitation-16580634http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16580634
http://purl.uniprot.org/uniprot/#_Q59FA7-mappedCitation-16580634http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16580634
http://purl.uniprot.org/uniprot/#_Q5ZEZ1-mappedCitation-16580634http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16580634