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http://purl.uniprot.org/citations/1658233http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1658233http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1658233http://www.w3.org/2000/01/rdf-schema#comment"An extract of the whole brain of the frog Rana ridibunda contained high concentrations of substance P-like immunoreactivity, measured with an antiserum directed against the COOH-terminal region of mammalian substance P and neurokinin B-like immunoreactivity, measured with an antiserum directed against the NH2-terminus of neurokinin B. The primary structure of the substance P-related peptide (ranakinin) was established as: Lys-Pro-Asn-Pro-Glu-Arg-Phe-Tyr-Gly-Leu-Met-NH2. Mammalian substance P was not present in the extract. The primary structure of the neurokinin B-related peptide was established as: Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2. This amino acid sequence is the same as that of mammalian neurokinin B. Ranakinin was equipotent with substance P and [Sar9,Met(O2)11]substance P in inhibiting the binding of 125I-Bolton-Hunter-[Sar9,Met(O2)11]substance P, a selective radioligand for the NK1 receptor, to binding sites in rat submandibular gland membranes (IC50 1.6 +/-0.3 nM; n = 5). It is concluded that ranakinin is a preferred agonist for the mammalian NK1 tachykinin receptor subtype."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.org/dc/terms/identifier"doi:10.1111/j.1471-4159.1991.tb06426.x"xsd:string
http://purl.uniprot.org/citations/1658233http://purl.org/dc/terms/identifier"doi:10.1111/j.1471-4159.1991.tb06426.x"xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Conlon J.M."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Conlon J.M."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Vaudry H."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Vaudry H."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Smith D.D."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Smith D.D."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Lovas S."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Lovas S."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"O'Harte F."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"O'Harte F."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Burcher E."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/author"Burcher E."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/name"J. Neurochem."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/name"J. Neurochem."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/pages"2086-2091"xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/pages"2086-2091"xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/title"Ranakinin: a novel NK1 tachykinin receptor agonist isolated with neurokinin B from the brain of the frog Rana ridibunda."xsd:string
http://purl.uniprot.org/citations/1658233http://purl.uniprot.org/core/title"Ranakinin: a novel NK1 tachykinin receptor agonist isolated with neurokinin B from the brain of the frog Rana ridibunda."xsd:string