| http://purl.uniprot.org/citations/1658800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1658800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1658800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1658800 | http://www.w3.org/2000/01/rdf-schema#comment | "Genomic RNA from the human prototype strain H of the hepatitis C virus (HCV-H) has been molecularly cloned and sequenced. The HCV-H sequence reported consists of 9416 nucleotides including the 5' and 3' untranslated regions. HCV-H shows 96% amino acid identity with the American isolate HCV-1 but only 84.9% with the Japanese isolates HCV-J and HCV-BK. In addition to the hypervariable region (region V) previously identified in the putative E2 domain, three other variable domains were identified: region V1 (putative E1), region V2 (putative E2), and region V3 (putative NS5). These regions appear rather conserved (86-100%) among the American isolates (HCV-1 and HC-J1) or among various Japanese isolates (HCV-J, HCV-BK, HCV-JH, and HC-J4) but show striking heterogeneity when the two subgroups are compared (42-87.5% amino acid difference). A structural similarity between the 5'-terminal hairpin structure of HCV and of poliovirus was observed. This study further suggests the existence of at least two genomic subtypes of HCV and confirms a distant relationship between HCV and pestiviruses."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.88.22.10292"xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.88.22.10292"xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.88.22.10292"xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Lee D.H."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Prince A.M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Prince A.M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Prince A.M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Inchauspe G."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Inchauspe G."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Inchauspe G."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Lee D.H.H."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Lee D.H.H."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Nasoff M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Nasoff M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Nasoff M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Sugitani M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Sugitani M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Sugitani M."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Zebedee S."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Zebedee S."xsd:string |
| http://purl.uniprot.org/citations/1658800 | http://purl.uniprot.org/core/author | "Zebedee S."xsd:string |