| http://purl.uniprot.org/citations/16603315 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16603315 | http://www.w3.org/2000/01/rdf-schema#comment | "Sequence variants of angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensinogen (AGT) T235M, angiotensin II type 1 receptor (AT1R) A1166C, and plasminogen activator inhibitor-1 (PAI-1) 4G/5G were analyzed to see their genetic associations with vascular dementia as its candidate genetic risk factors involving renin-angiotensin and fibrin systems. While the ACE I/D, AT1R A1166C, and PAI-1 4G/5G did not contribute to the genetic susceptibility to vascular dementia (P>0.05), a significant association with vascular dementia was shown in the T235M polymorphism of AGT. The frequency of the M allele in patients was higher than in controls with the odds ratio (OR) estimate of 1.51 (P<0.05). In a dominant model, the TM+MM genotypes increased the risk of vascular dementia compared to the TT genotype (OR=2.01; P<0.001). The current results suggested that AGT T235M polymorphism might be a risk factor of vascular dementia."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neulet.2006.03.035"xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/author | "Kim J.H."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/author | "Kim Y.J."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/author | "Kim Y."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/author | "Lee C."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/author | "Lee B.C."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/author | "Nam Y.J."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/author | "Yu K.H."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/pages | "276-279"xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/title | "Sequence variants of ACE, AGT, AT1R, and PAI-1 as genetic risk factors for vascular dementia."xsd:string |
| http://purl.uniprot.org/citations/16603315 | http://purl.uniprot.org/core/volume | "401"xsd:string |
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